Neurophysiological investigation of epilepsy
نویسنده
چکیده
Since its discovery in the late 1920s, the electroencephalogram (EEG) has developed into an array of digitally-based techniques, integrated with video and other investigative modalities that retain a central role in diagnosis and management of patients with seizure disorders. In contrast to the technological advances, relatively little progress has been made in understanding the cerebral generators of EEG signals, in part because of their anatomical complexity. Much of what appears on scalp EEG recordings represents the summation of synchronised excitatory or inhibitory post-synaptic potentials in apical dendrites of neurones in superficial neocortex, while deep generators may produce little or no change at the surface.
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